Potential function of miRNAs in herpetic stromal keratitis.

Effectiveness of levamisole on stromal herpetic keratitis.

Stromal herpetic keratitis has a poor prognosis. To date, corticosteroids appear to be the most efficatious agents against the condition. However, corticosteroids are immuno6uppresive, and may cause recurrences. The recent findings of decreased cellular immunity in the condition offer the possibility of using levamisole as the therapeutic agent. The present investigation was undertaken to evalu...

Nonspecific mitogen responses of peripheral lymphocytes in levamisole-treated patients with herpetic stromal keratitis.

For the purpose of determining the effect of levamisole on cell-mediated immunity of patients with herpetic stromal keratitis, the response of peripheral lymphocytes to three mitogens (PHA, Con A and PWM) was examined in a total of 19 cases of herpetic stromal keratitis (16 effective cases) including 12 patients undergoing levamisole administration. As controls, a similar study was made on 35 h...

Slitlamp biomicroscopy and photographic image analysis of herpes simplex virus stromal keratitis.

OBJECTIVE To validate photographic bioimaging for evaluating the severity of herpes simplex virus keratitis. METHODS Stromal keratitis of patients in the Herpetic Eye Disease Study was clinically measured with a slitbeam micrometer and then photographed at trial entry. Calibrated images of 169 eyes were analyzed for the size, location, and density of stromal keratitis and endotheliitis, with ...

Determination of Herpetic Keratitis Frequency Using Loop Mediated Isothermal Amplification (LAMP) Method in Isfahan, Iran

Herpetic keratitis which is resulted from herpes simplex virus type I, is considered the most common cause of corneal blindness that needs being diagnosed and treated in order to prevent irreversible eye effects. The best method to diagnose it is molecular method which has high sensitivity and exclusivity. The current study was done on 25 eye samples collected from patients referred to the Feyz...

Herpetic Stromal Keratitis Pathogenesis Stromal Keratitis: Possible Role for IL-1 in Antagonist Protein Are Resistant to Herpetic Mice Transgenic for IL-1 Receptor